The band has unveiled their first single in two years, "Ahimsa," ahead of their first-ever show in India next month.
For the occasion, U2 collaborated with award-winning Indian musician A.R. Rahman, who is best known for his work on the soundtrack for the 2008 "Slumdog Millionaire."
He notably composed the hit "Jai Ho," for which he earned two Academy Awards and two Grammys.
"Ahimsa," which is the Sanskrit word for non-violence, also features additional vocals by Rahman's daughters Khatija and Raheema.
In a recent interview with Rolling Stone India, Rahman opened up about the inspiration behind the U2's new collaborative song.
"The concept of 'ahimsa' or non-violence -- it's Indian, it's South Asian, it's Buddhist... and sometimes we have to remind people about love, about ahimsa. It takes a lot of courage to be non-violent. It takes a lot of power. It's not a weakness, it's more power than showing might; it's going beyond that, believing in something else which is not present... something that's only in your spirit," he explained.
"Ahimsa" arrives two years after U2's studio alb14thum, "Songs of Experience."
Since then, the band has reissued a slew of albums from their catalogue, including their 1985 "Wide Awake In America" EP, their 1997 "Pop" and their 2000 "All That You Can't Leave Behind."
U2 is currently touring across New Zealand as part of their mini Joshua Tree tour, which finds the group performing their 1987 landmark album in its entirety.
The group will later perform in Japan, Singapore, Seoul and Manila before concluding in Mumbai, India, on December 15.
According to Variety, U2 will also release four unspecified "highlights" from their catalogue of songs remixed by local Indian artists later this year.
In the meantime, discover "Ahimsa":