The Irish singer was set to play a few North American shows in 2018, but the concerts were ultimately postponed "due to unforeseen circumstances."
O'Connor, who now goes under the name of Magda Davitt, will embark on an extensive North American tour that will kick off February 2020.
The "Nothing Compares 2 U" singer will notably perform on February 1 at Vancouver's Vogue Theatre, with additional stops along the West Coast in Seattle, San Francisco and Los Angeles.
O'Connor will also perform multiple-night stands at City Winery locations in American cities such as Nashville, Atlanta, Philadelphia, Chicago and Boston.
The trek will wrap up in New York City after a three-night residency at City Winery from April 13 through 16. Tickets for the tour will go on sale on October 11 via the singer's website.
Over the past few years, O'Connor has faced some struggles with her family and mental health, admitting to TV host Dr. Phil that she had attempted to commit suicide on multiple occasions.
On August 2018, the Irish vocalist released her first song in four years, "Milestones," which she recorded with producer David Holmes.
"David wrote the music. I wrote the lyrics and melody. This is just a first demo for fans because they never get to hear a demo. I thought it would be fun to share it," she told the Irish Sun at the time.
O'Connor also hinted that she was working on her 11th studio effort, reportedly entitled "No Mud No Lotus," which would follow her 2014 "I'm Not Bossy, I'm the Boss."
She announced that the full-length would arrive at a yet-unknown date in late 2019.