The country superstar, who called East Nashville home for years, is partnering with Instagram resellers Stage to Closet for an online sale of items from her stage and daily-life wardrobe.
Musgraves pledged to donate all proceeds from the sale to Tennessee tornado relief, although they were originally set to benefit Tennessee urban forest preservation.
"Heartbroken for East Nashville. I lived on this side of town (in this neighborhood until recently) for years. Many friends are severely affected. Thankful to be ok and thinking of those who aren't," the multiple Grammy-winner wrote in her Instagram Stories.
She also added that, while forest preservation is an important issue, "the Nashville tornado relief efforts need help first."
According to local authorities, tornadoes touched down across Tennessee on Tuesday, March 3, killing at least 24 people and leaving an undetermined number missing.
The storms left about 50,000 homes and businesses without power, also destroying at least 48 buildings in the Nashville area.
Among them are one of the city's largest and most popular concert venues, the Basement East, which hosted a benefit for Democratic presidential candidate Bernie Sanders a few hours before the tornado hit.
The Basement East took to social media to announce that upcoming performances at the club have either been cancelled or relocated to other venues, adding that those at the venue "appreciate all the love and support from the Nashville community!"
According to The Tennessean, other celebrities have pledged to raise money to aid Nashville tornado relief.
Country star Chris Young announced that he will make a $50,000 donation to the Music City Inc. Foundation, while actress Reese Witherspoon confirmed that her Draper James store in Nashville's 12 South neighborhood will give all of its March 3 proceeds to the Community Foundation of Middle Tennessee.
Our thoughts are with all of the families who lost loved ones or have been devastated by the tornadoes. We will be donating 100% of today's proceeds to @CFMT's Middle Tennessee Emergency Response Fund to help those affected by the disaster #nashvillestrong pic.twitter.com/T82i6bwF9x— Draper James (@draperjames) March 3, 2020