Stipe has announced that he will release his first solo single, "Your Capricious Soul," on October 5.
The American singer has played "Your Capricious Soul" live on several occasions, performing it in May at New York's Webster Hall while he was opening for Patti Smith.
The single will be exclusively available for download on his website for 77 cents (USD), with all proceeds going to the climate activist group Extinction Rebellion.
In a statement, Stipe explained that the non-profit organization gave him the incentive to release his debut solo single after an eight-year hiatus from music.
"I want to add my voice to this exciting shift in consciousness. Extinction Rebellion gave me the incentive to push the release and not wait. Our relationship to the environment has been a lifelong concern, and I now feel hopeful -- optimistic, even. I believe we can bring the kind of change needed to improve our beautiful planet earth, our standing and our place on it," he said.
The former R.E.M frontman also revealed that an accompanying music video by English filmmaker Sam Taylor-Johnson will be released along with the single.
As Variety points out, Stipe revealed to the Italian newspaper La Repubblica earlier this year that he still has an album worth of new material up his sleeve.
"Eighteen songs are already ready. For five years, I'd had a clean break from music. Now I'm writing, composing, and recording all by myself and for the first time," he explained.
Stipe has yet to announce a release date for his forthcoming debut solo.